99.8 atom%D

Item number1025
Molecular weight44,07 g/mol
Quantity 1x25ml


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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 17.09.2021
Product name:Acetonitrile-d3
Catalog No.:1025
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Permoserstrasse 15

04318 Leipzig

Tel. +49 341 5295 183
Fax. +49 341 5295 182
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Flammable liquids (Category 2), H225
Acute toxicity, Oral (Category 4), H302
Acute toxicity, Inhalation (Category 4), H332
Acute toxicity, Dermal (Category 4), H312
Eye irritation (Category 2), H319
For the full text of the H-Statements mentioned in this Section, see Section 16.

F Highly flammable R11
Xn Harmful R20/21/22
Xi Irritant R36
Label elements
GHS07 exclam
Signal word Danger
Hazard statement(s)
H225 Highly flammable liquid and vapour.
H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled
H319 Causes serious eye irritation.
Precautionary statement(s)
P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P280 Wear protective gloves/ protective clothing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard
2.3 Other hazards - none
Synonyms : Trideuteroacetonitrile
Methyl-d3 cyanide
Hazardous ingredients
Component Classification Concentration
Flam. Liq. 2; Acute Tox. 4; Eye
Irrit. 2; H225, H302 + H312 +
H332, H319
<= 100 %
Molecular Weight (g/mol)44.07
FIRST AID MEASURES4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
no data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
no data available
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
Use water spray to cool unopened containers.
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to
form explosive concentrations. Vapours can accumulate in low areas.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and
place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature: 2 - 8 °C
7.3 Specific end uses
no data available
Components with workplace control parameters
Derived No Effect Level (DNEL)
Application Area Workers
Exposure routes Inhalation
Health effect Acute local effects, Acute systemic effects
Value 68 mg/m3
Application Area Workers
Exposure routes Skin contact
Health effect Long-term systemic effects
Value 32,2mg/kg BW/d
Application Area Workers
Exposure routes Inhalation
Health effect Long-term local effects, Long-term systemic effects
Value 68 mg/m3
Application Area Workers
Exposure routes Inhalation
Health effect Long-term local effects, Long-term systemic effects
Value 68 mg/m3
Application Area Consumers
Exposure routes Inhalation
Health effect Acute local effects
Value 220 mg/m3
Application Area Consumers
Exposure routes Inhalation
Health effect Acute systemic effects
Value 22 mg/m3
Application Area Consumers
Exposure routes Inhalation
Health effect Long-term systemic effects
Value 4,8 mg/m3

Predicted No Effect Concentration (PNEC)
Compartment Value
Water 10 mg/l
Soil 2,41 mg/kg
Marine water 1 mg/l
Fresh water 10 mg/l
Fresh water sediment 7,53 mg/kg
Onsite sewage treatment plant 32 mg/l

8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands
before breaks and at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and
approved under appropriate government standards such as NIOSH (US) or EN166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching gloves outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with
applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU)
2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which
differ from EN 374, contact the supplier of the CE approved gloves. This
recommendation is advisory only and must be evaluated by an industrial hygienist
and safety officer familiar with the specific situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use
Body Protection
Complete suit protecting against chemicals, Flame retardant antistatic protective
clothing., The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a fullface
respirator with multi-purpose combination (US) or type ABEK (EN 14387)
respirator cartridges as a backup to engineering controls. If the respirator is the sole
means of protection, use a full-face supplied air respirator. Use respirators and
components tested and approved under appropriate government standards such as
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: clear, liquid
Colour: colourless
b) Odour pungent
c) Odour Threshold No data available
d) pH No data available
e) Melting
point/freezing point
No data available
f) Initial boiling point
and boiling range
80,7 °C - lit.
g) Flash point 2,00 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid,
No data available
j) Upper/lower
flammability or
explosive limits
Upper explosion limit: 16,00 %(V)
Lower explosion limit: 4,40 %(V)
k) Vapour pressure 413,23 hPa at 55,00 °C
73,18 hPa at 15,00 °C
119,81 hPa at 25,00 °C
l) Vapour density No data available
m) Relative density 0,844 g/cm3 at 25 °C
n) Water solubility soluble
o) Partition coefficient:
log Pow: -0,340
p) Auto-ignition
No data available
q) Decomposition
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
Heat, flames and sparks.
10.5 Incompatible materials
acids, Bases, Oxidizing agents, Reducing agents, Alkali metalsStrong oxidizing agents
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen
oxides (NOx)
Other decomposition products - No data available
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 2.460 mg/kg
LC50 Inhalation - Rat - 8,00 h - 7551 ppm
Remarks: Behavioral:Altered sleep time (including change in righting reflex).
Behavioral:Convulsions or effect on seizure threshold. Blood: Hemorrhage.
LD50 Dermal - Rabbit - 2.000 mg/kg
Skin corrosion/irritation
Skin - Rabbit
Result: Mild skin irritation
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Irritating to eyes.
(OECD Test Guideline 405)
Respiratory or skin sensitisation
No data available
Germ cell mutagenicity
No data available
IARC: No component of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
Treat as cyanide poisoning., Always have on hand a cyanide first-aid kit, together with
proper instructions., The onset of symptoms is generally delayed pending conversion to
cyanide., Nausea, Vomiting, Diarrhoea
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
no data available
12.2 Persistence and degradability
no data available
12.3 Bioaccumulative potential
no data available
12.4 Mobility in soil
no data available
12.5 Results of PBT and vPvB assessment
no data available
12.6 Other adverse effects
no data available
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material
must be disposed of in accordance with the Directive on waste 2008/98/EC as well as
other national and local regulations. Leave chemicals in original containers. No mixing
with other waste. Handle uncleaned containers like the product itself.
ADR/RID: 1648 IMDG: 1648 IATA: 1648
14.2 UN proper shipping name
IATA: Acetonitrile
14.3 Transport hazard class(es)
14.4 Packaging group
14.5 Environmental hazards
ADR/RID: no IMDG Marine Pollutant: no IATA: no
14.6 Special precautions for user
no data available
REGULATORY INFORMATIONThis safety datasheet complies with the requirements of the regulation named on the first page of this SDS.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
15.2 Chemical Safety Assessment
no data available
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!