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Chloroform-d, cont. 0.03 v/v% TMS

99.8 atom%D

Item number1056
CAS865-49-6
FormulaCCl3D
Molecular weight120,38 g/mol
Quantity 10x0.75ml
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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 17.09.2021
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Chloroform-d, cont. 0.03 v/v% TMS
Catalog No.:1056
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Permoserstrasse 15

04318 Leipzig
Germany

Tel. +49 341 5295 183
Fax. +49 341 5295 182
E-mail: info@armar-europa.de
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
Acute toxicity, Inhalation (Category 3), H331
Skin irritation (Category 2), H315
Eye irritation (Category 2), H319
Carcinogenicity (Category 2), H351
Reproductive toxicity (Category 2), H361d
Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336
Specific target organ toxicity - repeated exposure, Oral (Category 1), Liver, Kidney, H372
Label elements
PictogramGHS06 skull
skull
GHS08 silhouete
silhouete
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram Signal word Danger
Hazard statement(s)
H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H331 Toxic if inhaled.
H336 May cause drowsiness or dizziness.
H351 Suspected of causing cancer.
H361d Suspected of damaging the unborn child.
H372 Causes damage to organs (Liver, Kidney) through prolonged or
repeated exposure if swallowed.
Precautionary statement(s)
P201 Obtain special instructions before use.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel
unwell.
P302 + P352 IF ON SKIN: Wash with plenty of water.
P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable
for breathing. Call a POISON CENTER/ doctor.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
Supplemental Hazard
Statements
none
For use in industrial installations only.
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Synonyms : Deuterochloroform
Formula : CCl3D
Molecular weight : 120,38 g/mol
CAS-No. : 865-49-6
EC-No. : 212-742-4
Component Classification Concentration
Chloroform-D1-Deuteration
Acute Tox. 4; Acute Tox.
3; Skin Irrit. 2; Eye Irrit.
<= 100 % 2; Carc. 2; Repr. 2; STOT
SE 3; STOT RE 1; H302,
H331, H315, H319, H351,
H361d, H336, H372
Concentration limits:
20 %: STOT SE 3, H336;
FormulaCCl3D
Molecular Weight (g/mol)120.38
CAS-No.865-49-6
FIRST AID MEASURES4.1 Description of first-aid measures
General advice
First aider needs to protect himself. Show this material safety data sheet to the doctor in
attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately
apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact
lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a
physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Hydrogen chloride gas
Not combustible.
Ambient fire may liberate hazardous vapours 5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by
keeping a safe distance or by wearing suitable protective clothing.
5.4 Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire
extinguishing water from contaminating surface water or the ground water system
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance
contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency
procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only
to qualified or authorized persons.
Store under inert gas. Light sensitive. hygroscopic
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters Components with workplace control parameters Component CAS-No. Value Control parameters
Basis
Chloroform-d
865-49-6
TWA 2 ppm
10 mg/m3
Europe. Commission Directive 2000/39/EC establishing a first list of indicative occupational exposure limit values Remarks Identifies the possibility of significant uptake through the skin Indicative
TWA
2 ppm
9.9 mg/m3
UK. EH40 WEL - Workplace Exposure Limits
Can be absorbed through skin. The assigned substances are those for which there are concerns that dermal absorption will lead to systemic toxicity. Where no specific short-term exposure limit is listed, a figure three times the long-term exposure should be used
8.2 Exposure controls Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching gloves outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid, clear
Color: colorless
b) Odor characteristic c) Odor Threshold No data available
d) pH No data available
e) Melting
point/freezing point
Melting point/range: -64 °C - lit.
f) Initial boiling point
and boiling range
60,9 °C - lit.
g) Flash point > 60 °C at ca.1.019,2 hPa - closed cup - Regulation (EC) No.
440/2008, Annex, A.9
h) Evaporation rate No data available
i) Flammability (solid,
gas)
No data available
j) Upper/lower
flammability or
explosive limits
No data available
k) Vapor pressure ca.265,31 hPa at ca.25 °C
l) Vapor density 4,12 - (Air = 1.0)
m) Relative density 1,500 g/cm3 at 25 °C
n) Water solubility 4,6 g/l at 20 °C - Regulation (EC) No. 440/2008, Annex, A.6
o) Partition coefficient:
n-octanol/water
log Pow: 1,5 at 20 °C - Bioaccumulation is not expected.
p) Autoignition
temperature
No data available
q) Decomposition
temperature
Distillable in an undecomposed state at normal pressure.
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available 9.2 Other safety information
Surface tension 72,3 mN/m at 0,99g/l at 20 °C
- Surface tension
Relative vapor
density
4,12 - (Air = 1.0)
STABILITY AND REACTIVITY10.1 Reactivity
No data available
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
no information available 10.5 Incompatible materials
Bases, Aluminum, Strong oxidizing agents, Magnesium, Sodium/sodium oxides, Lithium
10.6 Hazardous decomposition products
Other decomposition products - No data available
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen
chloride gas
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - male - 908 mg/kg
(OECD Test Guideline 401)
Skin corrosion/irritation
Skin - Rabbit
Result: Irritating to skin. - 24 h
Remarks: (ECHA)
Drying-out effect resulting in rough and chapped skin.
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Irritating to eyes.
Remarks: (ECHA)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative
(Regulation (EC) No. 440/2008, Annex, B.6)
Germ cell mutagenicity
Ames test
Salmonella typhimurium
Result: negative
(ECHA)
In vitro mammalian cell gene mutation test
mouse lymphoma cells
Result: positive
(ECHA)
Rat - male - Bone marrow
Result: positive
(ECHA) Carcinogenicity
Suspected of causing cancer.
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Chloroform-D1-Deuteration)
Reproductive toxicity
Suspected of damaging the unborn child.
Specific target organ toxicity - single exposure
May cause drowsiness or dizziness.
(in analogy to similar products) Specific target organ toxicity - repeated exposure
Oral - Causes damage to organs through prolonged or repeated exposure. - Liver, Kidney
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Aspiration hazard
No data available
Additional Information
RTECS: Not available
Vomiting, Gastrointestinal disturbance, Cough, irritant effects, Shortness of breath
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
ECOLOGICAL INFORMATION12.1 Toxicity
Toxicity to daphnia
and other aquatic
invertebrates
static test EC50 - Daphnia magna (Water flea) - 79 mg/l - 48 h
Remarks: (ECHA)
Toxicity to algae static test ErC50 - Chlamydomonas reinhardtii (green algae) - 13,3
mg/l - 72 h
Remarks: (ECHA)
Toxicity to bacteria static test EC50 - activated sludge - 0,48 mg/l - 24 h
Remarks: (ECHA)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 14 d
Result: 0 % - Not readily biodegradable.
(OECD Test Guideline 301C)
Theoretical oxygen
demand
1.346 mg/g
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Other adverse effects
No data available
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions
TRANSPORT INFORMATION14.1 UN number
ADR/RID: 1888 IMDG: 1888 IATA: 1888
14.2 UN proper shipping name
ADR/RID: CHLOROFORM
IMDG: CHLOROFORM
IATA: Chloroform
14.3 Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group
ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
REGULATORY INFORMATION15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
Authorisations and/or restrictions on use
REACH - Restrictions on the manufacture,
placing on the market and use of certain
dangerous substances, preparations and articles
(Annex XVII)
:
REACH - Restrictions on the manufacture,
placing on the market and use of certain
dangerous substances, preparations and articles
(Annex XVII)
: Chloroform-D1-Deuteration
Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or
stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!