99 atom%D

Item number1057-1X5ML
Molecular weight132,27 g/mol
Quantity 1x5ml
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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 29.02.2024
Product name:Cumene-d12
Catalog No.:1057-1X5ML
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Permoserstrasse 15

04318 Leipzig

Tel. +49 341 5295 183
Fax. +49 341 5295 182
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Flammable liquids (Category 3), H226
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
Aspiration hazard (Category 1), H304
Long-term (chronic) aquatic hazard (Category 2), H411
Label elements
GHS07 exclam
GHS08 silhouete
GHS09 Aquatic-pollut-red
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 Pictogram Signal word Danger
Hazard statement(s)
H226 Flammable liquid and vapor.
H304 May be fatal if swallowed and enters airways.
H335 May cause respiratory irritation.
H411 Toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P210 Keep away from heat, hot surfaces, sparks, open flames and
other ignition sources. No smoking.
P273 Avoid release to the environment.
P301 + P310 + P331 IF SWALLOWED: Immediately call a POISON CENTER/doctor. Do
NOT induce vomiting.
Supplemental Hazard
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
May form explosive peroxides.
Synonyms : Isopropylbenzene
Formula : C9H12
Molecular weight : 120,19 g/mol
CAS-No. : 98-82-8
EC-No. : 202-704-5
Index-No. : 601-024-00-X
Component Classification Concentration
Flam. Liq. 3; STOT SE 3;
Asp. Tox. 1; Aquatic
Chronic 2; H226, H335,
H304, H411
<= 100 %
Molecular Weight (g/mol)132.27
FIRST AID MEASURES4.1 Description of first-aid measures
General advice
Consult a physician. Show this material safety data sheet to the doctor in attendance If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse
mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Dry powder Dry sand
Unsuitable extinguishing media
Do NOT use water jet.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
Use water spray to cool unopened containers
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate
ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of
vapors accumulating to form explosive concentrations. Vapors can accumulate in low
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand,
earth, diatomaceous earth, vermiculite) and place in container for disposal according to
local / national regulations (see section 13). 6.4 Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of
electrostatic charge.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage. Store in cool place.
Recommended storage temperature 2 - 8 °C
Store under inert gas.
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION.1 Control parameters8.2 Exposure controlsEngineering measuresTechnical measures and appropriate working operations should be given priority over the use of personal protective equipment.See section 7.1.Individual protection measuresProtective clothing needs to be selected specifically for the workplace, depending on concentrations and quantities of the hazardous substances handled. The chemical resistance of the protective equipment should be enquired at the respective supplier.Hygiene measuresImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.Eye/face protection Safety glasses
Hand protection
The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374. This recommendation applies only to the product stated in the safety data sheet supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves. Other protective equipment:Flame retardant antistatic protective clothingRespiratory protectionrequired when vapours/aerosols are generated.Recommended Filter type:Filter A (acc. to DIN 3181) for vapours of organic compoundsThe entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.Environmental exposure controls Do not empty into drains. Risk of explosion.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid, clear
Color: colorless
b) Odor No data available
c) Odor Threshold No data available
d) pH No data available
e) Melting
point/freezing point
Melting point/range: -96 °C - lit.
f) Initial boiling point
and boiling range
152 - 154 °C - lit.
g) Flash point 31,0 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid,
No data available
j) Upper/lower
flammability or
explosive limits
Upper explosion limit: 6,5 %(V)
Lower explosion limit: 0,9 %(V)
k) Vapor pressure 10,7 hPa at 20,0 °C
l) Vapor density No data available m) Relative density 0,864 g/mL at 25 °C
n) Water solubility 0,06 g/l at 25 °C - slightly soluble
o) Partition coefficient:
log Pow: 3,55 at 23 °C
p) Autoignition
425,0 °C
q) Decomposition
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Surface tension 27,69 mN/m at 25 °C
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
Heat, flames and sparks.
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides
Other decomposition products - No data available
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
No data available
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation
(OECD Test Guideline 404)
Drying-out effect resulting in rough and chapped skin Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation - 72 h
(OECD Test Guideline 405)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative
(OECD Test Guideline 406)
Germ cell mutagenicity
Mutagenicity (mammal cell test): chromosome aberration.
Chinese hamster ovary cells
Result: negative
Ames test
Salmonella typhimurium
Result: negative
In vitro mammalian cell gene mutation test
Chinese hamster ovary cells
Result: negative
unscheduled DNA synthesis assay
rat hepatocytes
Result: negative
OECD Test Guideline 474
Mouse - male and female - Red blood cells (erythrocytes)
Result: negative
OECD Test Guideline 474
Rat - male - Bone marrow
Result: Positive results were obtained in some in vivo tests.
IARC: 2B - Group 2B: Possibly carcinogenic to humans (cumene)
Reproductive toxicity
No data available Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation. - Respiratory Tract
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Acute oral toxicity - gastric pain, Vomiting
Acute inhalation toxicity - mucosal irritations, Cough, Shortness of breath, Headache,
Nausea, Vomiting, Possible damages:, damage of respiratory tract
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
Aspiration may cause pulmonary edema and pneumonitis.
Additional Information
RTECS: GR8575000
narcosis, Central nervous system depression, Dermatitis, Gastrointestinal disturbance,
Damage to the lungs., Liver injury may occur., Kidney injury may occur.
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
After uptake of large quantities: somnolence, Dizziness, narcosis
Effect potentiated by: ethanol
Handle in accordance with good industrial hygiene and safety practice
Toxicity to fish flow-through test LC50 - Cyprinodon variegatus (sheepshead
minnow) - 4,7 mg/l - 96 h
Toxicity to daphnia
and other aquatic
static test EC50 - Daphnia magna (Water flea) - 2,14 mg/l - 48 h
(OECD Test Guideline 202)
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 2,01
mg/l - 72 h
(OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - > 2.000 mg/l - 3 h
(OECD Test Guideline 209)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 20 d
Result: 70 % - Readily biodegradable.
Remarks: (ECHA)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Other adverse effects
Toxic to aquatic life with long lasting effects.
Discharge into the environment must be avoided
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material
must be disposed of in accordance with the Directive on waste 2008/98/EC as well as
other national and local regulations. Leave chemicals in original containers. No mixing
with other waste. Handle uncleaned containers like the product itself.
Contaminated packaging
Dispose of as unused product.
ADR/RID: 1918 IMDG: 1918 IATA: 1918
14.2 UN proper shipping name
IATA: Isopropylbenzene
14.3 Transport hazard class(es)
14.4 Packaging group
14.5 Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA: no
14.6 Special precautions for user
No data available
REGULATORY INFORMATION15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
REACH - Restrictions on the manufacture,
placing on the market and use of certain
dangerous substances, preparations and articles
(Annex XVII)
REACH - Restrictions on the manufacture,
placing on the market and use of certain
dangerous substances, preparations and articles
(Annex XVII)
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!