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Acetophenone-d8

98 atom%D

Item number1029
CAS19547-00-3
FormulaC8D8O
Molecular weight128,20 g/mol
Quantity 1x5ml
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Safety Data Sheetaccording to Regulation (EC) No 1907/2006 (REACH)
Classifications according to Regulation (EC) No 1272/2008.
Printdate 17.09.2021
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:Acetophenone-d8
Catalog No.:1029
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards GmbH
Permoserstrasse 15

04318 Leipzig
Germany

Tel. +49 341 5295 183
Fax. +49 341 5295 182
E-mail: info@armar-europa.de
HAZARDS IDENTIFICATION2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
Eye irritation (Category 2), H319
Label elements
PictogramGHS07 exclam
exclam
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram Signal word Warning
Hazard statement(s)
H302 Harmful if swallowed.
H319 Causes serious eye irritation.
Precautionary statement(s)
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
Supplemental Hazard
Statements
none
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher
COMPOSITION/INFORMATION ON INGREDIENTS3.1 Substances
Formula : C8D8O
Molecular weight : 128,04 g/mol
CAS-No. : 19547-00-3
Component Classification Concentration
acetophenone-d₈
Acute Tox. 4; Eye Irrit. 2;
H302, H319
<= 100 %
FormulaC8D8O
Molecular Weight (g/mol)128.20
CAS-No.19547-00-3
FIRST AID MEASURES4.1 Description of first-aid measures
General advice
Consult a physician. Show this material safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse
mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed
No data available
FIRE-FIGHTING MEASURES5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
Use water spray to cool unopened containers
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate
ventilation. Remove all sources of ignition. Beware of vapors accumulating to form
explosive concentrations. Vapors can accumulate in low areas.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wetbrushing
and place in container for disposal according to local regulations (see section
13). Keep in suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13
HANDLING AND STORAGE7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of
electrostatic charge.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Store under inert gas. hygroscopic
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parameters Components with workplace control parameters 8.2 Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment

Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching gloves outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odor No data available
c) Odor Threshold No data available
d) pH No data available
e) Melting
point/freezing point
Melting point/range: 19 - 20 °C - lit.
f) Initial boiling point 202 °C - lit. and boiling range
g) Flash point 76,00 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid,
gas)
No data available
j) Upper/lower
flammability or
explosive limits
Upper explosion limit: 5,20 %(V)
Lower explosion limit: 1,40 %(V)
k) Vapor pressure 1 hPa at 15,00 °C
l) Vapor density No data available
m) Relative density 1,098 g/mL at 25 °C1,098 g/cm3 at 25 °C
n) Water solubility No data available
o) Partition coefficient:
n-octanol/water
log Pow: 1,600
p) Autoignition
temperature
No data available
q) Decomposition
temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available
STABILITY AND REACTIVITY10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
Heat, flames and sparks.
10.5 Incompatible materials
Strong oxidizing agents, Strong bases, Strong reducing agents
10.6 Hazardous decomposition products
No data available
Hazardous decomposition products formed under fire conditions. - Carbon oxides
In the event of fire: see section 5
TOXICOLOGICAL INFORMATION11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 815 mg/kg
Remarks: (RTECS)
LD50 Dermal - Rat - male and female - 3.300 mg/kg
(OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 24 h
(OECD Test Guideline 404)
slight irritation Possible damages: Dermatitis
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Irritating to eyes.
Remarks: (RTECS)
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
Mutagenicity (mammal cell test): chromosome aberration.
Chinese hamster lung cells
Result: positive
Mutagenicity (mammal cell test): chromosome aberration.
Chinese hamster lung cells
Result: negative
In vitro mammalian cell gene mutation test
mouse lymphoma cells
Result: negative
Ames test
Salmonella typhimurium
Result: negative
OECD Test Guideline 474
Mouse - male and female - Red blood cells (erythrocytes)
Result: negative
Carcinogenicity IARC: No ingredient of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Acute inhalation toxicity - Irritation symptoms in the respiratory tract.
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available Additional Information
Repeated dose toxicity - Rat - male and female - Oral - 90 Days - NOAEL (No observed
adverse effect level) - 250 mg/kg
RTECS: Not available
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice
ECOLOGICAL INFORMATION12.1 Toxicity
Toxicity to fish flow-through test LC50 - Pimephales promelas (fathead minnow) -
162 mg/l - 96 h
(OECD Test Guideline 203)
Toxicity to daphnia
and other aquatic
invertebrates
static test LC50 - Daphnia magna (Water flea) - 528 mg/l - 48 h
Remarks: (ECHA)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) -
86,4 mg/l - 72 h
(OECD Test Guideline 201)
Toxicity to bacteria static test IC50 - activated sludge - > 1.000 mg/l - 3 h
(OECD Test Guideline 209)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 14 d
Result: 64,7 % - Readily biodegradable.
(OECD Test Guideline 301C)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Other adverse effects
Discharge into the environment must be avoided
DISPOSAL CONSIDERATIONS13.1 Waste treatment methods
Product
This combustible material may be burned in a chemical incinerator equipped with an
afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed
disposal company.
Contaminated packaging
Dispose of as unused product.
TRANSPORT INFORMATION14.1 UN number
ADR/RID: - IMDG: - IATA: 3334
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Aviation regulated liquid, n.o.s. (acetophenone-d₈)
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: 9
14.4 Packaging group
ADR/RID: - IMDG: - IATA: III
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
REGULATORY INFORMATION15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!